Is Androstenedione Legal?

Is Androstenedione Legal?
Is Androstenedione Legal?

After the federal regulation of steroids were practitioners and researchers looking for the next big thing in athletic supplements. That came with the invention of pro-hormones. Androstenedione did pro-hormone popular by Mark McGwire is a precursor of testosterone and estrogen. The legality of this drug was forever changed after Congress passed the Anabolic Steroid Control Act of 2005. Androstenedione is illegal to distribute possess or use. Sales of androstenedinoe was banned in 2004 by the FDA.
History
The history of pro-hormones begins where the legality of steroids ends. As steroids became federally controlled substances individuals began again to search for replacement theirs. If production sales and administration of synthetic testosterone was illegal under federal law interested parties skirted intent of the law and took the next logical step to develop products that contained not testosterone but precursors of testosterone substances that the body can easily convert to bioavailable testosterone. The first of these substances to achieve widespread popularity in the United States was androstenedione. Androstenedione along with many other pro-hormones was made illegal by the 2005 amendments to the Anabolic Steroids Control Act.
effects
Androstenedione is a naturally occurring substance in the body. It is made by the adrenal glands and gonads in both men and women and is the precursor to both testosterone and estrogen. As a supplement androstenedione was shown to increase testosterone levels over an eight-hour period at a dose of 300mg a day. Estradiol levels also increased. Studies conducted in a daily dose of 50 mg 100mg and 300mg all showed no significant effect on body fat muscle size or strength.
side Effects
Although no known effect was seen on muscle size or strength did andro users experience estrogenic side-effects including increased risk of prostate cancer heart disease prostate enlargement lowered libido (in men) and the possibility of developing gynecomastia. On balance with zero real benefits and a number of adverse effects was androstenedione a swing and a miss.
Evolution
But androstenedione give birth to pro-hormone industry and led to the development of several other related substances that were successful. These substances come close to the effects of anabolic steroids while the potential for side effects. Two of these pro-hormone successes were 4-androstenediol (4-AD) and 19-nor-4-androstenediol both of which had about 80 percent of the effect of anabolic steroids and fewer side effects than the failed androstenedione.
Conclusion
The irony of the federal government’s stance against the use of anabolic steroids is that in passing the original Anabolic Steroid Act and prohibited these substances they created the impetus for the development of pro-hormones-substances that were not as effective but less dangerous than steroids . Not only pro-hormones have decreased efficiency coupled with undesirable side effects but the medical community has next to no established body of research on the long term effects of these newly developed compounds (unlike steroids which has existed since the 1930s). It is difficult to predict whether the next series of legal sports supplements will produce near numerous hazards caused by pro-hormone craze but it is a certainty that with the declaration of pro-hormones like androstenedione as banned substances we will soon find out.

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