The majority of choline in the body is in the form of phosphatidylcholine. Phosphatidylcholine is a phospholipid (fat phosphates attached) forming the cell membranes and very low-lipoprotein (VLDL). Fat and cholesterol consumed in the diet is packed in the liver to VLDLs. Without sufficient phosphatidylcholine, the VLDLs will accumulate in the liver and not be synthesized, resulting in liver damage. Adequate intake of phosphatidylcholine provides the essential nutrients and choline may have a variety of other health benefits.
Phosphatidylcholine is a phospholipid which is important in the formation and structural integrity of cell membranes. . It can also be metabolized in the cell to form the essential nutrient choline. Phosphatidylcholine is also used for production of VLDL, which transport fat from the liver to other tissues.
phosphatidylcholine may be isolated from egg or soy beans. Soy-based phosphatidylcholine is also referred to as soy lecithin. Lecithins generally contain a variety of other substances, but is a rich (20 percent to 90 percent) source of phosphatidylcholine.
When the supply of choline and phosphatidylcholine is low, VLDLs not synthesized and fats accumulate in the liver, which can lead to liver damage. Choline and phosphatidylcholine-deficient individuals also have reduced blood levels of “good” cholesterol LDL.
intake of lecithin inhibits the absorption of dietary cholesterol. The combination of this effect, as well as mobilization of fat in the liver, have indicated that phosphatidylcholine could promote lipolysis, or the breakdown of fat. Introduced medically to treat fatty liver, cosmetic mesotherapy injections of phosphatidylcholine is also developed for the treatment of localized fat.
Use of phosphatidylcholine in mesotherapy is the subject of some debate. The main points in this debate focusing on mesotherapy itself. Several clinical studies actually indicate that phosphatidylcholine injections are effective alone or in combination with drugs (e. G., Deoxycholate) to reduce localized fat deposits.
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